Pharmacology of anaesthetic agents II: inhalation anaesthetic agents
نویسندگان
چکیده
منابع مشابه
Toxicity of inhalation anaesthetic agents.
Although hundreds of compounds on the chemist's shelf are known to produce anaesthesia, relatively few are used clinically. The requirements for a clinically useful anaesthetic agent are necessarily stringent and include: a wide margin of safety, total reversibility of anaesthetic effect and an absence of long-term toxicity. In addition, a successful inhalation anaesthetic agent must combine th...
متن کاملAnaesthetic potency of inhalation agents is independent of membrane microviscosity.
The decrease in membrane microviscosity of erythrocyte ghosts in the presence of clinically relevant concentrations of seven inhalation anaesthetic agents was studied using fluorescence polarization anisotropy of the membrane incorporated fluorescent probes 1,6-diphenyl-1,3,5-hexatriene and 1-[4-trimethylammoniumphenyl]-6-phenyl-1,3,5-hexatriene. All anaesthetic agents produced a dose-dependent...
متن کاملAspects of the pharmacology of local anaesthetic agents.
The use of local anaesthetic techniques varies with the anaesthetist's working conditions, direction of interest, and hence geographically. Thus they are mainly used in certain centres in America and Canada, and in the Scandinavian countries. Interest in, and use of, local anaesthesia has increased during the last decade. There are many reasons for this. The use of these techniques enables the ...
متن کاملAdverse reactions to anaesthetic agents.
Sir,—Even though some small changes in heart rate were shown to be statistically significant, no clinical significance was attached to such changes. The study was primarily done to assess the overall need of anticholinergic premedication in patients undergoing minor surgery and as such drugs were not administered on a weight basis. However, Dr Gilmour's comment has aroused our interest in this ...
متن کاملPotency of mixtures of general anaesthetic agents.
The anaesthetic potencies of binary mixtures of the gases argon (Ar), nitrous oxide (N2O) and sulphur hexafluoride (SF6) have been measured using mice. The mixtures SF6-N2O and N2O-Ar showed additive behaviour, whereas the constituents of the mixture SF6-Ar were non-additive, having a smaller total potency than expected. Further experiments on this mixture with Italian Great Newts and on the ca...
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ژورنال
عنوان ژورنال: Continuing Education in Anaesthesia Critical Care & Pain
سال: 2014
ISSN: 1743-1816
DOI: 10.1093/bjaceaccp/mkt038